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Overall, the available evidence suggests that semaglutide poses minimal risk to liver health in the general population and may offer benefits for patients with fatty liver disease through its weight loss effects

Fatigue was slightly more likely with semaglutide, while injection site reactions were reported more with tirzepatide

[DOI] [PMC free article] [PubMed] [Google Scholar] 107.Kusama H, Kon K, Ikejima K, Arai K, Aoyama T, Uchiyama A, Yamashina S, Watanabe S.Sodium 4-phenylbutyric acid prevents murine acetaminophen hepatotoxicity by minimizing endoplasmic reticulum stress

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