Preclinical Models of Cocaine and Psychostimulant Use Disorders Cocaine and related psychostimulants such as amphetamines exert their addictive potential primarily via enhanced dopaminergic signaling in mesolimbic circuits, particularly through increased dopamine availability in the NAc
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Besides neurons, astrocytes and microglia express GLP-1Rs (see Vrang and Larsen, 2010 for a general overview) (Merchenthaler et al., 1999
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