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It is important to maintain adequate fluid intake and to seek medical attention if you experience significantly reduced urine output or symptoms of severe dehydration

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In my functional medicine practice, Ive identified several patient populations who may benefit from a microdosing approach: Individuals Seeking Modest Weight Loss Not everyone needs to lose 50 pounds

Similarly, in controlled clinical studies in patients with type 2 diabetes mellitus, the antihyperglycemic effect of metformin was comparable in males and females

The highest dose currently being studied in major Phase 3 obesity trials is 12mg once weekly