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In a separate head-to-head comparison, GHK-Cu outperformed both retinol (vitamin A) and vitamin C in improving skin firmness and elasticity, and it did so without the irritation, photosensitivity, or adjustment period associated with retinoid use

They are not a sedative or a benzodiazepine, so they do not usually cause strong drowsiness or dependence

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[PMC free article: PMC7230874] [PubMed: 32244279] 51

Some of the studies that have been done have given mixed results