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Yu CE, Oshima J, Fu YH, et al

Moreover, SFN treatment significantly reduced the overall PASI score compared with the IMQ group, indicating the protective effects of SFN on psoriasis

Estrogen has also been found to reverse chemotherapy resistance of ovarian cancer by targeting the Nrf2/GPX4 signaling axis to induce ferroptosis in drug-resistant human epithelial ovarian cancer cells (74)

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These combined effects position FOXO4-DRI as a promising therapeutic strategy for combating age-related diseases and dysfunction (1)