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Medications such as semaglutide and dulaglutide consistently demonstrate HbA1c reductions of 1.0-1.5% (11-16 mmol/mol) in people with type 2 diabetes
October 8, 2022
"Retatrutide for the treatment of obesity, obstructive sleep apnea and knee osteoarthritis: Rationale and design of the TRIUMPH registrational clinical trials." 2025
Retatrutide Who Should NOT Use It Contraindications (Based on Research & Trial Exclusions) 1) Personal/family history of medullary thyroid carcinoma (MTC) or MEN2 Similar medications in the GLP-1 receptor agonist class list this as a contraindication due to observed thyroid C-cell tumors in rodent studies and exclusion from trials
Back Couzin-Frankel, J (22 Sept 2023), 'Sidelined', Science , 381/6664, 1274-77
How They Differ in Practice The textbook differences are easy to list
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