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Mitochondrial reactive oxygen species (mROS), the byproduct of mitochondrial energy generation, serves as an essential mediator to control the activation and differentiation of cells and regulate the antigenicity of oxidized nucleoids within the mitochondria

It is likely that female-specific changes in protein expression also occur in ibuprofen treated livers and these changes were not investigated

(2004) 286:G4918

Yes, from a mechanistic standpoint, they are complementary