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Free Radic Biol Med 39:5849, PMID: 16085177 Richards RS, Roberts TK, Dunstan RH, McGregor NR, Butt HL (2000) Free radicals in chronic fatigue syndrome: cause or effect

So, stable and safe delivery systems become necessary

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The body can finally downregulate its stress response and enter parasympathetic (rest-and-digest) mode instead of remaining in sympathetic (fight-or-flight) activation

Berberis vulgaris contains considerable levels of berberine

GPX4 and GSH, as important intracellular antioxidants, protect cells from ferroptosis