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Retatrutide is developed by Eli Lilly and Company, the same company that makes tirzepatide (Zepbound and Mounjaro)

The fiber in avocados can slow digestion, leading to a more gradual release of glucose into the bloodstream

These side effects can be intense enough for an estimated 10% to 20% of patients to stop using GLP-1s, and they tend to be dose dependent meaning that the higher the dose, the more intense or frequent the side effects can be

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In August 2025, Novo Nordisk announced that the FDA has approved WEGOVY as the first GLP-1 receptor agonist for adults with Metabolic Dysfunction-associated Steatohepatitis (MASH) who have moderate to advanced fibrosis, excluding cirrhosis, in combination with diet and exercise