Similar content being viewed by others Introduction Tumor multidrug resistance (MDR) is the core clinical challenge responsible for the failure of antitumor therapy, disease recurrence, and even patient death
3.4.4.2 Prebiotics In a male rat model of PTSD-like symptoms induced via amygdala hyperactivation (a key pathophysiological mechanism of PTSD)3 weeks of treatment with the prebiotic GOS restored microbial homeostasis by enriching beneficial Bifidobacterium animalis and Limosilactobacillus reuteri , while eliminating harmful Enterococcus casseliflavus (Ruciski et al., 2025)
Some analytical systems have been developed for its detection and quantification [138]
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Research Gaps & Future Directions Current studies primarily use cell/animal models more human trials are needed to explore: PQQs dual role in cancer (antioxidant vs