But that changed with the approval and launch of the Wegovy pill in December 2025 and then again with the launch of Foundayo in April 2026
Conclusion Nausea can be one of the more challenging side effects of GLP-1 medications, but with the right strategies in place, it is manageable
doi: 10.1016/j.neuropharm.2013.08.005 159 HolubovaMHrubaLPopelovaABenczeMPrazienkovaVGenglerSet al
NICE guidance does not mandate preference for daily versus weekly formulations but recommends individualising treatment choice based on patient factors including: Lifestyle and convenience : Weekly injections may suit busy schedules Tolerability : Some patients experience fewer gastrointestinal side effects with certain formulations Clinical efficacy : Specific medications may provide better glucose control or weight loss for individual patients Cost-effectiveness : NHS formularies may influence availability Your GP or diabetes specialist nurse will discuss which dosing schedule best suits your circumstances, taking into account your treatment goals and personal preferences
24 , 10291037 (2022) J.F.E
Since its launch in 2021, the cost has fallen from over $1,000 a month to $650, $499, and is now $349