Receptor Activity Comparison GLP-1 Receptor Primary Effects: Appetite suppression, insulin secretion, gastric emptying delay Relevance to Bulking: Controls caloric intake, improves nutrient timing GIP Receptor Primary Effects: Enhanced insulin response, fat metabolism, nausea reduction Relevance to Bulking: Better nutrient partitioning, improved tolerance Glucagon Receptor Primary Effects: Increased energy expenditure, fat oxidation, thermogenesis Relevance to Bulking: Preferential fat burning, metabolic rate support The GLP-1 receptor activation provides appetite regulation that many lifters find invaluable during body composition phases
Large randomized trials designed to detect rare adverse events are mostly absent in this area
Is the dose too high
Seth-Vollenweider T, Joshi S, Dhawan P, Sif S, Christakos S
[DOI] [Google Scholar] 81.Fujiwara S., Ishizuka H., Fudano S
take 2 capsule a day