Quick Answer: Most patients see blood glucose improvements within 14 weeks of starting GLP-1 therapy, while noticeable weight loss typically becomes apparent after 46 weeks, with peak effects at 6072 weeks
high blood pressure, type 2 diabetes)
Some may contain stimulants like caffeine or synephrine that can cause increased heart rate, anxiety, or sleep problems
A meta-analysis [74] including the ELIXA [66], LEADER [44], SUSTAIN-6 [67], EXSCEL [68], REWIND [70], and AMPLITUDE-O [51] studies found that GLP-1RAs were associated with better renal outcomes: a 30% or 40% or more decrease in glomerular filtration rate, need for renal replacement therapy, end-stage renal failure, or death from kidney disease by 21%
Telogen effluvium is self-limiting
They are another option in the anti-resorptive category, particularly for postmenopausal women for whom bisphosphonates may not be appropriate