Risk ratios (RR) for nonfatal myocardial infarction estimates according to direct (DPP-4 inhibitors, GLP-1RA and SGLT-2 inhibitors against placebo) and indirect (DPP-4 inhibitors vs GLP-1RA or SGLT-2 inhibitors, and GLP-1RA vs SGLT-2 inhibitors) comparisons
any acceleration of net price declines beyond current guidance would compress the revenue line before volume catches up
WADA will be judging semaglutide against their three-pronged banning test
Update: Plaintiffs Request that Ozempic-Related Vision Loss Cases Be Consolidated in New Jersey On June 12, 2025, five law firms representing 21 plaintiffs alleging GLP-1-related injuries submitted a letter to the Administrative Office of the Courts requesting that their lawsuits be designated as a Multicounty Litigation (MCL) in New Jersey State Court
Semaglutide 2.4 mg (Wegovy) showed 14.9% average body weight loss over 68 weeks in the STEP 1 trial
The broad search algorithm combined index terms and free-text words for all GLP-1-RAs, with no restriction to study language, design (including both individual studies and their meta-analyses), setting, comparator and outcome of interest to maximize the comprehensiveness of the evidence synthesis
