Cancer-associated fibroblasts modulate growth factor signaling and extracellular matrix remodeling to regulate tumor metastasis
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In this, pentadecapeptide BPC 157 consistently (grossly, microscopically, and biomechanically) cured burn injuries, and counteracted corticosteroid (6-methylprednisolone 1.0 or 10 mg/kg/day ip for 21 days)-induced impairment of burn healing (Sikiric et al., 2003)
Critics argue that the FDA's caution could restrict access to a potentially beneficial compound, advocating for a more balanced approach that considers BPC-157's therapeutic potential
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