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Based on Phase 2 data, the general titration pathway for those targeting the 12 mg maintenance dose appears to proceed as follows

Currently, studies of GLP-1s for PCOS are inconclusive due to small sample population and heterogenicity between trials

The majority of people who discontinue due to side effects do so during this window

It is important to note that, following the UK's departure from the European Union, European Medicines Agency (EMA) authorisations do not apply in Great Britain

Can I take a GLP-1 receptor agonist with metformin or insulin

The titration schedule in the clinical trial was a minimum timeline, not a mandate