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S Afr J Bot 148:415436 Lama YC, Ghimire SK, Aumeeruddy-Thomas Y (2001) Medicinal plants of Dolpo

Opioid-Induced Hyperalgesia (OIH) occurs when an opioid analgesic paradoxically causes an increase in pain, or an increase in sensitivity to pain

That finding led to further studies and eventually to the development of Contrave , a combination of bupropion and another medication called naltrexone, approved by the FDA for weight management

Firstly, GLP-1 affects appetite levels, insulin secretion, and stomach emptying speed, all of which can impact nutrient status in the shortand long-term

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Do not use if the safety seal is damaged or missing.