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Typical Retatrutide Titration Schedule 1mg weekly 2mg weekly 4mg weekly 8mg weekly (if tolerated) 12mg weekly (maximum dose) Note: Slower escalation is acceptable if side effects are significant

It is this ratio, in particular, that distinguishes retatrutide from other triple agonists in development (such as survodutide, currently in Phase 3 trials at Boehringer)

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In anticipation of this publication, a mathematical model was developed, and the results of the SOUL trial are predicted by this study

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