Metformin, lifestyle modification, and symptom-specific treatments (combined oral contraceptives, anti-androgens) remain first-line PCOS management per NICE guidance
174 Previous studies have reported the comprehensive effects of GLP-1RA on the CNS, which go beyond the levels of blood glucose modulation, but are associated with numerous metabolic aspects such as food intake and preference, 127,175 water intake, 176 energy expenditure, 177 body weight reduction, 178 pancreatic function, 132,179,180 hypertension, 181 stress, 182 addiction behaviors, 183,184 as well as neurodegenerative disorders, such as Alzheimer and Parkinson diseases
The radioprotective potentials of silymarin/silibinin against radiotherapy-induced toxicities: a systematic review of clinical and experimentalstudies
Clin Transl Allergy
Smaller, more frequent meals Four to five smaller eating occasions tend to be easier to manage than three large meals, especially in the first weeks of adjusting to a lower appetite
Thats a mystery facing patients and their doctors these days
