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HCH, hypertensive cerebral hemorrhage

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Gao S, Zhou L, Lu J, Fang Y, Wu H, Xu W, Pan Y et al (2022) Cepharanthine attenuates early brain injury after subarachnoid hemorrhage in mice via inhibiting 15-lipoxygenase-1-mediated microglia and endothelial cell ferroptosis

doi: 10.5501/wjv.v10.i2.34 69 DrgeW

Sustained microglial activation leads to the release of pro-inflammatory cytokines such as TNF-, IL-1, and IL-6, which exacerbate neuronal injury and amplify amyloid and tau pathology (Kaur et al., 2019)