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The Mechanism: Stopping the Wave: Migraines are driven by an electrical wave (Cortical Spreading Depression)

More specifically, its linked to duodenal ulcers, which are a type of peptic ulcer that occurs in the small intestine

Another important miRNA regulating cell metabolism is miR-378/378*, embedded within gene encoding peroxisome proliferator-activated receptor gamma coactivator 1-beta (PGC-1), a transcriptional regulator of oxidative energy metabolism

doi: 10.1093/brain/aws059 213 ZhangR

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Dallagnol, J