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Semaglutide works by mimicking a hormone called GLP-1 (glucagon-like peptide-1), which helps regulate blood sugar levels and appetite

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Longer exposure, combined with full-dose maintenance after titration, produces substantially deeper weight loss

IGF1 LR3 is often preferred for studies needing sustained receptor start, systemic effects, or protocols where frequent use would be impractical

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BMI of 30 or higher , or 27 or higher with weight-related conditions such as type 2 diabetes, high blood pressure, or high cholesterol Adults seeking medical weight loss support under professional supervision Patients committed to diet and exercise changes alongside treatment Individuals able to attend follow-up care and ongoing monitoring Semaglutide may not be appropriate during pregnancy or breastfeeding , and treatment suitability should be determined through consultation with a qualified healthcare provider