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Key ones include pregnancy, uncontrolled hypertension, glaucoma (phentermine), seizure disorders (bupropion component of Contrave), and significant cardiovascular disease history

Fluoxetine (20 mg/kg, s.c.) coadministered with cannabis (5 mg/kg, s.c.) resulted in significant decrease in the immobility time by the day 21 of the study compared with the cannabis only group

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If the pain doesnt improve with basic measures, worsens over time, or is accompanied by other concerning symptoms such as numbness, tingling, or weakness, its essential to seek medical advice promptly

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