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Pernicious anemia can develop from a lack of a protein that

Poor dietary intake of B12-rich foods, such as meat, fish, and dairy products, is one of the most common causes of vitamin B12 deficiency

This enzyme catalyzes the N-methylation of nicotinamide using S-adenosyl-L-methionine (SAM) as a methyl donor, effectively creating a "metabolic drain" that depletes both NAD+ precursors and cellular methylation capacity

While these claims align with the proposed mechanisms , its important to set realistic expectations for outcomes

People with a family history of vitamin B12 deficiency

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