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After a treatment period of 3 months, to test the effectiveness of treatment as part of usual clinical care, vitamin B12 levels, activity meter, and questionnaires were repeated

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However, mAb treatment tended to oppose age-related changes in 30 of these metabolites (22 marginally significant after FDR correction), including a reduction in the age-related rise of many glycerophospholipids, and a distinct clustering of metabolites from heart tissue in Old Con versus Old mAb-treated animals by PCA (Supplementary Fig

10.1016/j.heliyon.2022.e09575 [DOI] [PMC free article] [PubMed] [Google Scholar] Prez-Sala D., Pajares M