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doi: 10.1126/scitranslmed.aav1648 174 ArbitmanLFurieRVashisthaH

Since GLP-1Rs are absent in human skeletal muscle, effects must be indirect

This is supported by recent studies from US and German adults with T2D, which reported that the use of GLP-1RAs versus insulin resulted in lower emergency room visits and inpatient admissions but higher drug acquisition costs after treatment initiation [49, 50]

Do we really need another GLP-1 drug

Is There Any Risk to Health