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After full recovery, correct cannulation was tested by observing water drinking responsiveness after infusion of 1 l human angiotensin II (Sigma-Aldrich, A9525) at a concentration of 24 M in artificial cerebrospinal fluid (distilled water with 125 mM NaCl, 2.5 mM KCl, 2.6 mM NaHCO 3 , 1.25 mM NaH 2 PO 4 2H 2 O, 25 mM d-glucose monohydrate, 1 mM MgCl 2 , 2 mM CaCl 2 )

Metabolic phenotypes in animal models of DPP4 deficiency Insight into the metabolic consequences of reduced or absent DPP4 activity came from animal models with inactivating mutations in DPP4

The gut microbiome is integral to the development and functioning of the HPA axis, which regulates neuroendocrine responses and manages stress [149]

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I (Alex Cook, part of Primes newsroom team) connected with Ben Urick, PharmD, senior director of health outcomes, and Landon Marshall, PharmD, health outcomes research principal, who presented at the conference and serve as authors on the latest cost-of-care research to learn more about the studies and their experience at the conference