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The study also showed increased pro-MMP-9 expression, indicating active cartilage remodeling
Dosing for maintenance in vegetarians (without confirmed deficiency): 250 mcg per day, or 2,500 mcg once weekly
However, this often means taking supraphysiological doses, which may increase the risk of side effects like joint swelling and insulin resistance
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In any case they should not worry anyone undergoing slow withdrawal
Oral B-12 supplements effectiveness depends on consistency and absorption
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