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GSSH can also donate its sulfur atom to proteins forming protein persulfides [52]

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Figure 13 summarizes key intracellular glutathione (GSH) sensing strategies, encompassing fluorescent probes that detect reduced GSH through light emission, enzymatic biosensors that generate electrical signals via GSHNAD(P)H redox cycling, quantum nanoprobes that enable high-resolution fluorescence shifts, and nanomaterial-based sensors that act as GSH-responsive reporters for gene editing and signal amplification

Curcumin attenuates acute inflammatory injury by inhibiting the TLR4/MyD88/NF-kappaB signaling pathway in experimental traumatic brain injury