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The sprays are based on aqueous solutions of the anti-helminthic drug niclosamide, a drug with relatively low water solubility at pH 7 (and hence prohibitively low bioavailability)

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Discussion We characterized fornix and hippocampus integrity in EP patients and observed altered diffusion and volumetric properties in the fornix and hippocampus, respectively

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Statistically significant effects were followed up with pairwise comparisons using the Tukey adjustment to account for multiple comparisons