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And at the molecular level, GLP-1 receptor agonists appear to directly inhibit platelet aggregation, reduce inflammatory markers, and improve endothelial function, all of which should theoretically protect against clots

Histological analysis (as assessed via Masson and picrosirius red staining) highlighted a significant improvement in extracellular matrix fibrosis of the CD5/ LNP treatment group than the saline, IgG/ LNP or PFD groups (Fig

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The milligram dosing represents a reasonable extrapolation from animal research using standard interspecies scaling factors