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The opposing effects of GIP and GLP-1 on lipogenesis and lipolysis, respectively, help maintain adipocytes in young and healthy state, fostering higher levels of adiponectin a key adipokine known for its potential antidiabetic, anti-inflammatory, and antiatherogenic properties (185)

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When done appropriately and monitored through a medical provider, it can provide a great benefit to not only assist weight loss but promote overall health, without having to worry about loss of muscle or negative impact to overall health, even with long term use. Curious About Trying HRT and GLP-1s Together