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Surgery also typically requires medication adjustments always handled individually by a doctor

Danuglipron and orforglipron are nonpeptide oral GLP-1R agonists in development that have shown encouraging safety and efficacy in glycemic control among patients with T2DM [179]

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The AACE/ACE Obesity Clinical Practice Guidelines state directly: "Obesity is a chronic, relapsing disease process" requiring treatment strategies comparable in duration to those used for hypertension or type 2 diabetes [4]

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