In order to prevent this phenomenon, catalase (another antioxidant enzyme) which is abundant in the peroxisomes breaks down H2O2 into water and molecular oxygen, consequently curtailing free radical-induced damage (Fig
The main difference is duration of action, not the core mechanism
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Other prevalent GI adverse events included constipation (30.4%, 95% CI: 29.531.3%), diarrhea (32.7%, 95% CI: 29.531.3%), nausea and vomiting (23.4%, 95% CI: 22.624.2%), GI bleeding (15.9%, 95% CI: 15.216.6%), gastroparesis (5.1%, 95% CI: 4.65.5%), and pancreatitis (3.4%, 95% CI: 3.03.7%)