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This just means it's linked into a 3D mesh network that lets it be more stable and sit on skin as a cohesive, gel-like film rather than sinking into skin

But this process is way more complex than that, especially involving the thyroid hormone

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To determine co-localization of the various GFP constructs and the GM130 signal, an area covering the whole perinuclear region but excluding the PM was selected in confocal images and the Pearsons correlation was calculated using the co-localization tool of ImageJ v1.53c

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