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Smoking : Tobacco puts toxins and free radicals into your lungs and bloodstream, leading to inflammation and decreased lung function

Every time athletes exert themselves, the body converts increased oxygen to energy, releasing free radicals that steal electrons from healthy cells and tissues

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Arsenic: One reason we need glutathione is to detoxify arsenic

While necessary, this phase transforms toxins into "reactive intermediate metabolites" that are frequently more toxic and volatile than the original substance, generating massive amounts of free radicals