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248 Importantly, renal hypoxia is found not only during the acute phase of AKI but also up to 5 weeks later, after the recovery phase

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It occurs naturally in human cells, where it is one of the body's principal intracellular antioxidants and a substrate in several detoxification pathways

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After absorption, the substance undergoes conjugation by liver enzymes such as UDP-glucuronosyltransferases (UGTs) and sulphotransferases (SULTs), forming inactive metabolites that further reduce its plasma concentration and limit its distribution to target tissues [53]