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This study found that GLP-1 treatment had a 2.11 HR of developing wet AMD: 0.2% of GLP-1 treated patients developed wet AMD compared to 0.1% of control

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For example, the UK Summary of Product Characteristics (SmPC) for Wegovy (semaglutide 2.4 mg) includes a precautionary note in Section 4.4 advising healthcare professionals to monitor patients for suicidal ideation and behaviour, particularly those with a history of psychiatric disorders

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The remaining trials (TRIUMPH-2/-3/-4 and TRIUMPH-Outcomes) are still anticipated through 20262028