"Bypasses the Barrier" Isn't the Same as "More Effective" It's mechanically true that injection delivers a peptide past the stratum corneum, the skin barrier that limits how much of anything applied topically actually gets through
This effect is relevant not only in neurodegenerative pathology but also in aging, where brain inflammation is chronically elevated ( In prior studies, the antioxidant, anti-inflammatory, and anti-apoptotic properties of AST have been reported to improve the quality of life in diseases ranging from cancer to neurodegenerative diseases
212222, www.ncbi.nlm.nih.gov/pmc/articles/PMC9377173/, Weschawalit, Sinee, et al
A review of research trends in physiological abnormalities in autism spectrum disorders: immune dysregulation, inflammation, oxidative stress, mitochondrial dysfunction and environmental toxicant exposures
Understanding the differences between these peptides is crucial for clinicians and researchers alike, as it enables informed decision-making regarding their use in specific clinical contexts
Front Cell Dev Biology, 2024 ;12:1461278