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Regulatory Status AOD-9604 is not an FDA-approved drug for any indication and has not been shown to be safe or effective for any human use

The agency would need the Justice Department's help to pursue an injunction, as it lacks independent litigation authority, Hawana said

Current staging strategies involve routine tumor testing for BRAF and PD-1

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Internalization experiments validated receptor-mediated endocytosis, resulting in cytoplasmic accumulation, while in vivo imaging demonstrated significant tumor targeting and retention, with aptamer Levels in tumors being 50 to 1000 times greater than in other tissues

K., McClelland, E