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Introduction Hydroxymethylglutaryl-coenzyme A reductase (HMG-CR) inhibitors, commonly known as statins, are indicated for hypercholesterolemia and atherosclerotic cardiovascular diseases (Sizar et al., 2019)

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Using multiple high-throughput proteomics assays in two independent cohorts of konzo-affected children compared to unrelated individuals (Discovery) or their unaffected sibling (Validation) respectively, we demonstrate that levels of the critical plasma-based antioxidant enzyme Glutathione Peroxidase 3 (GPx3) are significantly reduced in those affected

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Estrada LV, Watman D, Franzosa E, Reckrey J

Needle angle during water injection, injection rate, and dissolution time without agitation