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Data Availability RNA sequencing data are accessible online at Mendeley Data ( Acknowledgements We thank Tim Stearns for help with confocal imaging, Edo Biluar for reading the manuscript and assisting with experiments, and Julien Sage and Jan Carette for providing reagents

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Multiple Scler J 17:289296 Lovell MA, Ehmann WD, Butler SM, Markesbery WR (1995) Elevated thiobarbituric acid-reactive substances and antioxidant enzyme activity in the brain in Alzheimer's disease