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KEAP1/NRF2 mutant cells are protected against cysteine-starvation induced ferroptosis due to elevated GCLC expression and limited glutamate accumulation, and dual targeting of cystine import and GCLC activity can overcome the resistance of NRF2 active cells to ferroptosis (Kang et al., Cell Metab 2021)

Biotin Based on 28 publication(s) in Google Scholar Biotin, vitamin B7 and serves as a coenzyme for five carboxylases in humans, involved in the synthesis of fatty acids, isoleucine, and valine, and in gluconeogenesis

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