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2024 Jun 12;15(6):e0067924

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Furthermore, HRMS-based non-targeted analyses using MS/MS structural elucidation allowed to identify other relatively minor metabolites related to APAP-Cys such as S-(5-acetylamino-2-hydroxyphenyl)mercaptopyruvic acid (SAMP), an APAP metabolite potentially formed by the transamination reaction of APAP-cysteine (see Fig.1), previously observed in mouse ( 29 )

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Throughout that process, Shawn and his team was busy working on the regulatory and scientific side of things, doing everything right