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In the U.S., prescriptions for these drugs among obese patients jumped from 21,000 in 2019 to 174,000 in 2023

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Advantages include a clear side effect profile, since any reactions are attributable to semaglutide alone rather than combination ingredients

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The reduction of tumor-draining lymphatic vessel contraction could lead to the elevation of interstitial fluid pressure in primary tumor sites (119, 120), which might drive cancer cells to migrate toward functional lymphatic vessels that are mainly positioned in the tumor margin (68)