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Cytokine suppression profile: Research data documents that KPV produces statistically significant reductions in TNF- (3045%), IL-6 (2540%), and IL-1 (2035%) in inflamed colonic tissue in preclinical models

This dual mechanismboth substrate delivery and gene activationexplains the strong antioxidant effect of GHK-Cu, which exceeds what would be achievable through simple copper supplementation alone

All other reagents not previously specified are from Aladdin unless otherwise stated

doi: 10.1111/jfbc.14461 115

Kulkarni, S

Tunable nanoparticles with aggregationinduced emission heater for precise synergistic photothermal and thermodynamic oral cancer therapy of patientderived tumor xenograft