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This is consistent with the previous findings that hypoxia-response genes were upregulated in the islets of diabetic, but not prediabetic, db/db mice in an inverse relationship with unfolded protein response gene expression 28,33

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Its one of the most important compounds in the body for staying healthy, says Joel Evans, MD, a member of the core faculty at the Institute for Functional Medicine and founder and director of the Center for Womens Health in Stamford, Conn