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Nausea Vomiting Diarrhea Stomach discomfort Reduced appetite In rare cases, more serious complications such as severe hypoglycemia may occur, particularly when used with other diabetes medications

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Moreover, ingestion of d-allulose suppressed food intake without altering water intake, urine volume and osmolality, creatinine excretion, glucose excretion, and electrolytes (Na + , K + , and Cl ) excretion (Supplementary Fig