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32 Tirzepatide, a GLP-1R-GIPR co-agonist, exhibits superior insulin responses and potent glucose-lowering and weight-loss effects compared to existing GLP-1R agonists

doi: 10.1038/s43856-024-00566-z, 135 SorensenG.ReddyI

doi: 10.3390/POLYM14040735 127 NilssonA

Carla Alessandra Scorza has received funding from The National Council for Scientific and Technological Development (CNPq #302583/2017-3)

Systematic review: predictive biomarkers of therapeutic response in inflammatory bowel diseasepersonalised medicine in its infancy

Moderate ROS can reinforce PI3K/AKT/mTORC1 activation, whereas excessive accumulation induces oxidative stress and inactivates key components, shifting the balance toward cell death [48, 49]