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The mechanosensitive disc cells responded with an up-regulation of different anabolic but also catabolic genes such as aggrecan, TIMP-1, ADAMTS-4, MMP-3 and MMP-13

Follicles came from the occipital (back) scalp the region least affected by androgenetic alopecia

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This interaction reduces inhibitory binding between caveolin-1 and endothelial nitric oxide synthase, allowing increased enzyme activity and nitric oxide production in endothelial cells

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